One-year Follow-up after US-guided Transperineal Focal Laser Ablation of Localized Prostate Cancer: Worldwide Registry Study

< .001), with 83% sensitivity and 89% specificity. Conclusion In this multicenter study, MRI-directed, US-guided TPLA of 206 localized PCa lesions resulted in a 12-month csIFR rate of 17%. Post-TPLA positive MRI findings were highly predictive for csIFR. ClinicalTrials.gov identifier: NCT05163197 © RSNA, 2026