Effects of different bypass surgeries on LSA revascularization in patients with left subclavian occlusion

医学 闭塞 血运重建 心脏病学 颈总动脉 锁骨下动脉 血流动力学 搭桥手术 内科学 血流 锁骨下盗血综合征 外科 动脉 颈动脉 心肌梗塞
作者
Da Li,Xiangguo Zeng,Jiarong Wang,Ding Yuan,Tinghui Zheng
出处
期刊:International Journal for Numerical Methods in Biomedical Engineering [Wiley]
卷期号:38 (9) 被引量:1
标识
DOI:10.1002/cnm.3636
摘要

Abstract Introduction Left subclavian artery (LSA) bypass surgery is mainly carried out for patients with severe left subclavian occlusion. This article aimed to evaluate the hemodynamic effects of different surgical bypass modes on LSA revascularization. Methods Three‐dimensional models of the aorta were reconstructed from CTA images of a patient with LSA occlusion, a patient with type B aortic dissection with LSA coverage during thoracic endovascular aortic repair, and a healthy 74‐year‐old man, resulting in six modes for each person: healthy LSA mode, LSA occlusion mode and four bypass modes. Hemodynamic parameters, including flow field, flow distribution, pressure gradient, and wall shear stress, were calculated using computational fluid dynamics. Results After LSA bypass surgery, distal LSA blood flow resulting from left common carotid artery (LCCA) to distal LSA bypass was 100% of that in the healthy mode, while the other modes yielded flows at least 91%. Moreover, reversed flow only completely disappeared with LCCA to distal LSA bypass, whereas reverse flow was observed in the other three modes in early systole. Conclusion Left common carotid artery to distal LSA bypass can effectively reduce reverse blood flow in the left vertebral artery, and it is a feasible, effective, and safe option for LSA revascularization in patients with left subclavian occlusion.

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