肝内胆管癌
巨噬细胞极化
重编程
MAPK/ERK通路
生物
癌症研究
细胞生物学
巨噬细胞
信号转导
极化(电化学)
肿瘤相关巨噬细胞
M2巨噬细胞
磷酸化
癌变
下调和上调
作者
Aimaiti Yasen,Yichen Tang,Xiaomin Yang,Guohua Zuo,Jun Feng,Guoying Wang,Lu Zheng
标识
DOI:10.1016/j.yexcr.2025.114845
摘要
IL-33/ST2 signaling drives ICC progression by promoting M2 macrophage polarization via the MAPK pathway. Targeting this axis may represent a novel therapeutic strategy for ICC.
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