A national cohort study examined the risk of severe infection and infection-related mortality in patients with chronic kidney disease with lupus nephritis in comparison to other chronic kidney disease etiologies

Patients with LN exhibited a higher risk of severe infection compared to patients with ANCA vasculitis, ADPKD and PGD. LN-CKD and DKD had similar infection-risks. This highlights the need for prevention and tailored immunosuppressive therapy in the LN-population with CKD.