化学
分子内力
酞
亚硝酸盐
催化作用
基质(水族馆)
光化学
氢键
组合化学
表面改性
药物化学
高分子化学
有机化学
分子
物理化学
地质学
硝酸盐
海洋学
作者
Miaomiao Hu,Jiangyu Yang,Mengyu Niu,Chunmei Li,Xu Meng,Meichao Li,Zhenlu Shen
出处
期刊:Synlett
[Georg Thieme Verlag KG]
日期:2023-10-04
摘要
Abstract A functionalization of benzylic C(sp3)–H bonds was established through a mild metal-free intramolecular lactonization protocol in the presence of DDQ/tert-butyl nitrite as photocatalysts, allowing practical and low-cost access to a series of phthalide products in moderate to excellent yields. Compared with many existing methodologies, this visible-light-driven process exhibits an excellent substrate scope and fascinating features, including the formation of water as the sole byproduct, an abundant and green energy source, commercially available catalysts, and room-temperature reaction. Finally, detailed mechanistic investigations clearly revealed the role of the photocatalysts and molecular oxygen.
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