Crystallisation and Preliminary X-Ray Diffraction Studies on Human Liver Aldolase

Human liver aldolase has been crystallised from an over-expressed protein in the space group 1212121 with unit cell dimensions a = 189.0 A, b = 59.5 A and c = 155.2 A, α = β= γ= 90°. The strncture has been solved by molecular replacement at 3.8 A resolution using human muscle aldolase as an initial model.