生物传感器
计算生物学
DNA
纳米技术
化学
生化工程
计算机科学
生物
材料科学
生物化学
工程类
作者
Chunran Ma,Shiquan Li,Yuqi Zeng,Yifan Lyu
出处
期刊:Biosensors
[MDPI AG]
日期:2024-05-08
卷期号:14 (5): 236-236
摘要
The rise of DNA nanotechnology has driven the development of DNA-based molecular machines, which are capable of performing specific operations and tasks at the nanoscale. Benefitting from the programmability of DNA molecules and the predictability of DNA hybridization and strand displacement, DNA-based molecular machines can be designed with various structures and dynamic behaviors and have been implemented for wide applications in the field of biosensing due to their unique advantages. This review summarizes the reported controlling mechanisms of DNA-based molecular machines and introduces biosensing applications of DNA-based molecular machines in amplified detection, multiplex detection, real-time monitoring, spatial recognition detection, and single-molecule detection of biomarkers. The challenges and future directions of DNA-based molecular machines in biosensing are also discussed.
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