The Tanyu Tongzhi Formula enhances IL-10 expression and macrophage efferocytosis to alleviate atherosclerosis in mice

IL-10-mediated efferocytosis potentiation is the critical pathway through which TTF stabilizes atherosclerotic plaques. The NF-κB/IL-10/efferocytosis axis provides a novel pharmacological target for macrophage-directed anti-atherosclerotic therapies. Tanyu Tongzhi Formula participates in the above regulatory mechanism and significantly alleviates atherosclerosis.