体细胞突变
B细胞
免疫球蛋白基因
生物
抗体
淋巴瘤
滤泡性淋巴瘤
免疫球蛋白重链
免疫学
作者
Michael S. Khodadoust,Niclas Olsson,Binbin Chen,Brian J. Sworder,Tanaya Shree,Chih Long Liu,Lichao Zhang,Debra K. Czerwinski,Mark M. Davis,Ronald Levy,Joshua E. Elias,Ash A. Alizadeh
出处
期刊：Blood
[Elsevier BV]
日期：2018-12-14
卷期号：133 (8): 878-881
被引量：48
标识
DOI：10.1182/blood-2018-06-845156
摘要
TO THE EDITOR:
Non-Hodgkin B-cell lymphomas are almost invariably derived from B lymphocytes that have undergone productive V(D)J rearrangements of their immunoglobulin genes and may additionally have experienced somatic hypermutation. In the case of follicular lymphomas, malignant clones undergo
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