生物
河马信号通路
再生(生物学)
细胞生物学
疾病
信号转导
神经科学
病理
医学
作者
Yonggang Zheng,Duojia Pan
标识
DOI:10.1016/j.devcel.2019.06.003
摘要
The Hippo signaling pathway regulates diverse physiological processes, and its dysfunction has been implicated in an increasing number of human diseases, including cancer. Here, we provide an updated review of the Hippo pathway; discuss its roles in development, homeostasis, regeneration, and diseases; and highlight outstanding questions for future investigation and opportunities for Hippo-targeted therapies.
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