Design, Synthesis and Evaluation of Mucin Glycopeptide Based Cancer Vaccine

Immunotherapy is one of the most effective techniques for the treatment of diseases. Anti-tumor vaccines have been widely researched. Mucin glycopeptides are considered to be one of the most promising antigens for anti-tumor vaccines. Mucin glycopeptides have weak immunogenicity and numerous immune-stimulating structures have been incorporated through chemical synthesis. In this chapter, we mainly focus on the mucin-based glycopeptide antitumor vaccines, including their design, synthesis and evaluation.