This study was designed to assess the Adverse drug reactions (ADRs) reported to tertiary care teaching hospital. A total of 174 ADRs, reported during 1 year period among which Dermatology department reported maximum 131 (75%). Most common ADRs reported were acneiform eruptions [n=61, 35.05%]. Among the total ADRs, topical steroids [n=60, (34.48%)] were responsible for most of the reactions followed by antimicrobial drugs and NSAIDs [n=20, (20.69%)] each. The causality of maximum ADRs were probable 148 (85.05%) with the suspected reaction. This study strongly suggests that there is a greater need for streamlining of hospital based ADR reporting and monitoring system to create awareness so that majority of ADRs can be prevented.