Recently, IHT(intermittent hypoxia training)has been a highlight in the international academia of sports medicine.Hypoxia can be divided into two sorts in terms of the damage.One is dysoxia and the other is adapted cell hypoxia. Furthermore,IHT can also be defined as chronic hypoxia and intermittent hypoxia according to the training time .We introduce a variety of hypoxia training models and the hypoxia adaption of skeletal muscle and draw the conclusion that the cell signaling mechanisms in adaptions in IH is the future direction of research.