Cognition is a process that reflects or conceptually represents the reality in human mind. No matter which is concerned, the self or the world where one lives, human cognition and his knowledge feature incertitude. The limits of cognition show that neither cognition-as-process nor cognition-as-status could evade the problem of cognition possibility. Intrinsically, the limits of cognition and possibility of individual cognition both result from separation of subject and object and opposition of mind and body. Therefore, settlement of mind-body problem is central to the problems above.