Clinical analysis of multiple organ dysfunction syndrome complicated with hypoalbuminemia

Objectives:To study the clinical features of multiple organ dysfunction syndrome(MODS) complicated with hypoalbuminemia. Methods:80 cases of MODS whose APACHE Ⅱ was from 17 to 18 were selected and devided into two groups according to existance of peritoneal infection or not. Results:The occurrence rate of hypoalbuminemia was 73.8% in the 80 cases. The rate was 97.0% in the group complicated with peritoneal infection,with the lowest level occurring on the second day and being (24± 3.5 )g/L, and 57.4% in the group without peritoneal infection,with the lowest level occurring on the seventh day and being (35±2.9)g/L.There were very marked differences between the two groups( P 0.01 ).The mortality rate of the patients with hypoalbuminemia was 49.1%,being much higher than that in the cases without hypoalbuminemia(23.8%)( P 0.05). Conclusions:The occurrence rate of hypoalbuminemia is higher in the severe patients.There are marked differences in occurrence rate,occurrence time,and decreasing level of hypoalbuminemia between the group complicated with peritoneal infection and the group without peritoneal infection.The decreasing level of plasma albumin correlates closely with the prognosis of the patients with MODS.