Inhibition of cGAS-STING Pathway via an Endogenous Copper Ion-Responsive Covalent Organic Framework Nanozyme for Alzheimer's Disease Treatment

Inhibition of cGAS-STING overactivation has recently emerged as a promising strategy to counteract Alzheimer's disease (AD). However, current cGAS-STING inhibitors as immunosuppressants suffer from instability, non-specific targeting, and innate immune...