The key new techniques in the medicinal chemist’s toolkit to prioritize solubility during drug design

Future Medicinal ChemistryVol. 14, No. 20 EditorialThe key new techniques in the medicinal chemist’s toolkit to prioritize solubility during drug designPooja Sahu & Rajnish KumarPooja SahuRoyal College of Pharmacy, Raipur, Chhattisgarh, IndiaSearch for more papers by this author & Rajnish Kumar *Author for correspondence: E-mail Address: rajnish.phe@iitbhu.ac.inhttps://orcid.org/0000-0002-7021-6996Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, 221005, U.P., IndiaSearch for more papers by this authorPublished Online:27 Sep 2022https://doi.org/10.4155/fmc-2022-0225AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: bioisosterism and prodrug approachescrystal packing disruptionheterocyclic modificationssolubilitystructural modificationReference1. 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Molecules 21, 42–73 (2016).Crossref, Google ScholarFiguresReferencesRelatedDetails Vol. 14, No. 20 Follow us on social media for the latest updates Metrics Downloaded 52 times History Received 11 September 2022 Accepted 15 September 2022 Published online 27 September 2022 Published in print October 2022 Information© 2022 Newlands PressKeywordsbioisosterism and prodrug approachescrystal packing disruptionheterocyclic modificationssolubilitystructural modificationFinancial & competing interests disclosureThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download