餐后
抑制性突触后电位
糖尿病
肽
药理学
生物利用度
生物化学
医学
化学
生物
内分泌学
作者
Lu Han,Tiantian Xie,Qi Wu,Zuomin Hu,Yi Luo,Feijun Luo
出处
期刊:Nutrients
[MDPI AG]
日期:2023-10-05
卷期号:15 (19): 4267-4267
被引量:2
摘要
With the change in people’s lifestyle, diabetes has emerged as a chronic disease that poses a serious threat to human health, alongside tumor, cardiovascular, and cerebrovascular diseases. α-glucosidase inhibitors, which are oral drugs, have proven effective in preventing and managing this disease. Studies have suggested that bioactive peptides could serve as a potential source of α-glucosidase inhibitors. These peptides possess certain hypoglycemic activity and can effectively regulate postprandial blood glucose levels by inhibiting α-glucosidase activity, thus intervening and regulating diabetes. This paper provides a systematic summary of the sources, isolation, purification, bioavailability, and possible mechanisms of α-glucosidase inhibitory peptides. The sources of the α-glucosidase inhibitory peptides were introduced with emphasis on animals, plants, and microorganisms. This paper also points out the problems in the research process of α-glucosidase inhibitory peptide, with a view to providing certain theoretical support for the further study of this peptide.
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