Recent Advances in Ligand Engineering for Gold Nanocluster Catalysis: Ligand Library, Ligand Effects and Strategies

Abstract Advances in new ligands in the last decade facilitated in‐depth studies on the property‐relationship of gold nanoclusters and promoted the rational synthesis and related applications of such materials. Currently, more and more new ligands are being explored; thus, the ligand library of AuNCs is being expanded fast, which also enables investigation of ligand effects of AuNCs via direct comparison of different ligating shell with the identical gold core. It is now widely accepted that ligands influence the properties of AuNCs enormously including stability, catalysis, photoluminescence among others. These studies inspired ligand engineering of AuNCs. One of the goals for ligand engineering is to develop ligated AuNC catalysts in which the ligands are able to exert big‐enough influence on electronic and steric control over catalysis as in a transition‐metal or an enzyme system. Although increasing attention is paid to the further expansion of ligand library, the investigation of design principles and strategies regarding ligands are still in their infant stage. This review summarizes the ligands for AuNC synthesis, the ligand effects on stability and catalysis, and recently developed strategies in promoting AuNC catalytic performance via ligand manipulation.