Supplementary Revised Figure S4 from MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53

Stable knockdown of TSPYL5 in lung cancer cells. A, MUC16 expression was significantly elevated in cisplatin resistant cell line. To determine the TSPYL5 role in lung cancer, we stably knocked down TSPYL5 in H292 cells. B, Upon TSPYL5 knockdown, the expression of p53 was increased as compared to scramble cells. C, Knockdown of TSPYL5 was also confirmed by QPCR analysis. β-actin was used as loading control. **P<0.01.