Figure S1 from Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates
作者
Niña G. Caculitan,Josefa Chuh,Yong Ma,Donglu Zhang,Katherine R. Kozak,Yichin Liu,Thomas H. Pillow,Jack Sadowsky,Tommy K. Cheung,Qui Phung,Benjamin Haley,Byoung-Chul Lee,Robert W. Akita,Mark X. Sliwkowski,Andrew G. Polson
<p>Supplementary Figure 1: Loss of cathepsin B in cells. Cathepsin B enzymatic assays for various gRNAs tested against cathepsin B in KPL-4 cells (A) and BT-474M1 (B). IP/WB for cathepsin B expression in KPL-4 cells (C) and BT-474M1 (D). Change in mRNA expression of cathepsin B in BJAB and WSU-DLCL2 cells.</p>