果糖
蔗糖
糖
氧化应激
黑腹果蝇
玉米糖浆
食品科学
高果糖玉米糖浆
活性氧
甜叶菊
生物
DNA损伤
化学
甜菊
雷巴迪甙A
人造甜味剂
生物化学
甜菊苷
DNA
基因
医学
替代医学
病理
作者
Ghada Tagorti,Burçin Yalçın,Merve Güneş,Ayşen Yağmur Burgazlı,Bülent Kaya
标识
DOI:10.1080/01480545.2023.2228522
摘要
The overconsumption of added sugars makes people vulnerable to a myriad of diseases. Several biochemical and developmental assays were performed in the current study to assess the effect of fructose on Drosophila melanogaster and to find substitutes for fructose by comparing it to well-known sweeteners. Drosophila was exposed separately to the same ratio of sugar 9.21% (w/v) of several types of sweeteners (sucrose, fructose, glucose syrup, high-fructose corn syrup and stevia). Results revealed that fructose might induce recombination, whereas stevia lacks genotoxic potential. No developmental delay, growth defects, or neurotoxic effects were recorded for any of the sweeteners. We also observed no striking differences in reactive oxygen species levels. Thus, stevia seems to be an alternative sweetener to fructose that can be consumed to reduce fructose-induced anomalies.
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