生物
肺炎克雷伯菌
乳腺炎
微生物学
病菌
系统发育树
克雷伯菌
病毒学
遗传学
基因
大肠杆菌
作者
Qianhui Ma,Zhaoxuan Zhu,Yue Liu,Jia Wang,Zihao Pan,Huochun Yao,Jiale Ma
标识
DOI:10.1016/j.micinf.2023.105106
摘要
Klebsiella pneumoniae (Kp) is now recognized as an urgent threat to public health since the emergence of multidrug-resistant and hypervirulent isolates. We identified a hypervirulent K2 isolate from the milk samples possibly associated with an infection incident in children, which raised the alarm to the zoonotic potential of bovine mastitis Kp as a foodborne pathogen. Subsequently, numerous K1, K2, K3, K5, K54 and K57 strains were identified from mastitis milk samples, and showed high pathogenicity in infected mouse. Further analysis based on complete genomes found that these isolates showed closely evolutionary relationships with the human hypervirulent strains in diverse phylogenetic lineages, suggesting their potential risk to public health.
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