Management of ALL in Adults: 2023 ELN Recommendations from a European Expert Panel
医学
家庭医学
作者
Nicola Gökbuget,Nicolas Boissel,Sabina Chiaretti,Hervé Dombret,Michael Doubek,Adele K. Fielding,Robin Foà,Sebastian Giebel,Dieter Hoelzer,Mathilde Hunault,David I. Marks,Giovanni Martinelli,Oliver G. Ottmann,Anita W. Rijneveld,Philippe Rousselot,Josep‐María Ribera,Renato Bassan
出处
期刊:Blood [American Society of Hematology] 日期:2024-02-02
标识
DOI:10.1182/blood.2023023568
摘要
Experts from the European Leukemia Net (ELN) working group for adult acute lymphoblastic leukemia have identified an unmet need for guidance regarding management of adult ALL from diagnosis to aftercare. The group has previously summarized their recommendations regarding diagnostic approaches, prognostic factors and assessment of ALL (cross-reference). The current recommendation summarizes clinical management. It covers treatment approaches including the use of new immunotherapies, application of MRD for treatment decisions, management of specific subgroups and challenging treatment situations as well as late effects and supportive care. The recommendation provides guidance for physicians caring for adult ALL patients which has to be complemented by regional expertise preferably provided by national academic study groups. -