纳米探针
生物相容性
纳米技术
赫拉
体内
纳米材料
荧光
化学
材料科学
体外
生物物理学
纳米颗粒
临床前影像学
肿瘤细胞
癌症治疗
实体瘤
癌症研究
量子点
荧光寿命成像显微镜
作者
Xinyue Kou,Juan Yue,Yingge Cong,Ruoqian Gao,Wenfei Dong,Li Li
出处
期刊:Small
[Wiley]
日期:2026-05-03
卷期号:: e73637-e73637
摘要
. In vitro studies demonstrated excellent biocompatibility and efficient cellular uptake, with preferential localization in lysosomes. In vivo experiments in HeLa tumor-bearing mice revealed effective tumor accumulation via the enhanced permeability and retention (EPR) effect, enabling high-contrast NIR-II fluorescence and MR imaging. These results highlight the great potential of B@AIE NPs as a promising metal-free nanoprobe for precise tumor diagnosis through FL/MR dual-modal imaging.
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