One pot synthesis of palladium-cobalt nanoparticles over carbon nanotubes as a sensitive non-enzymatic sensor for glucose and hydrogen peroxide detection

A non-enzymatic electrochemical sensor based on in situ formed palladium-cobalt nanoparticles supported over carbon nanotubes (Pd-CoCNTs) was developed for both glucose and hydrogen peroxide detection. Pd-CoCNTs were synthesized by a one-pot pyrolysis process. Transmission electron microscope (TEM) images revealed well distributed palladium nanoparticles (PdNPs) on the Pd-CoCNTs surface with diameters of 2–4 nm. Benefitting from the insitu formed PdNPs, the as-prepared glucose sensor displayed satisfactory performance with sensitivity, selectivity and long-term stability. The linear range for glucose determination was 10 μM–2.4 mM with a detection limit of 1 μM. The hydrogen peroxide sensor was also studied and showed a wide linear range with a detection limit of 0.3 μM. The proposed glucose sensor was successfully used in blood plasma analysis and showed satisfactory results.