Recent advance in cerebral organoids

The 3D human brain organ is an in vitro cultured organ that can be implemented by a researcher in recent years in a standard tissue culture chamber. Its growth and development is very similar to the endogenous developmental program of the human brain. The 3D human brain organs can promote people's understanding of human brain characteristics, and thus, conduct more in-depth research on human brain neuropsychiatric diseases. This is a review of the development, application, obstacles and prospects of 3D human brain organs. Key words: 3D in vitro culture; Cerebral organoid; Alzheimer's disease