核糖核酸
计算生物学
功能(生物学)
RNA结合蛋白
细胞生物学
模块化设计
核糖开关
生物
生物化学
非编码RNA
计算机科学
基因
操作系统
作者
Bradley M. Lunde,Claire Moore,Gabriele Varani
摘要
Many RNA-binding proteins have a modular structure and are composed of multiple repeats of a few small RNA-binding domains. By arranging the domains in various ways, these proteins can carry out their diverse biological roles in an RNA-specific manner. Many RNA-binding proteins have modular structures and are composed of multiple repeats of just a few basic domains that are arranged in various ways to satisfy their diverse functional requirements. Recent studies have investigated how different modules cooperate in regulating the RNA-binding specificity and the biological activity of these proteins. They have also investigated how multiple modules cooperate with enzymatic domains to regulate the catalytic activity of enzymes that act on RNA. These studies have shown how, for many RNA-binding proteins, multiple modules define the fundamental structural unit that is responsible for biological function.
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