Objective To study the efficacy of treatment of refractory chronic prostatitis with TURP. Methods Fourteen patients with refractory chronic prostatitis treated by TURP were followed up, the indication of operation TURP technique and surgical results were analyzed. Results Among the fourteen patients,10 were cured,2 improved, a total efficacy of 85%. No serious complication was observed. Conclusion TURP is an effective therapy for refractory chronic prostatitis