Effects of celery seed powder on blood lipid and liver function in high fat-diet rats

Objective To explore the effects of celery seed powder on blood lipid parameters and liver function.Methods 50 male Wistar rats were randomly divided into 5 groups:normal feed group,high fat feed group.Celery seed powder group at the dose of 1.0,2.0,3.0 g/(kg·bw) administered intragastrically.30 days later,the serum total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),alanine transaminase(ALT),aspertate transaminase(AST) content are determined.Results The serum TC,TG and LDL-C in 2.0 g/kg and 3.0 g/kg group were significantly lower,HDL-C had no change,ALT,AST content were significantly declined compared with those in model group.Conclusion Celery seed powders have certain regulatory effect on blood lipid and liver function.