纳米材料
纳米技术
分析物
生物传感器
纳米颗粒
材料科学
免疫分析
化学
作者
Daniel Quesada-González,Amadeo Sena-Torralba,Wiyogo Prio Wicaksono,Alfredo de la Escosura-Muñiz,Tribidasari A. Ivandini,Arben Merkoçi
标识
DOI:10.1016/j.bios.2019.02.049
摘要
Lateral flow biosensors are paper-based devices that allow the detection of different types of analytes with quickness, robustness and selectivity, without leaving behind paper sensors benefits as low-cost, recyclability and sustainability. Nanomaterials have been widely reported in lateral flow biosensors, offering new sensing strategies based on optical or electrical detection techniques. Looking for other advantageous nanomaterials, we propose for the first time the use of iridium oxide (IV) nanoparticles in lateral flow assays for the detection of human immunoglobulin as a model protein. These nanoparticles can be easily prepared and conjugated with biomarkers. Their dark blue color gives a high contrast against the white background of the strips being in this way excellent labels.
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