酮洛芬
乙基纤维素
化学
纤维素
壳体(结构)
聚醋酸乙烯酯
化学工程
纳米颗粒
芯(光纤)
核化学
高分子化学
材料科学
色谱法
有机化学
复合材料
聚合物
纳米技术
工程类
作者
Pu Wang,Menglong Wang,Xi Wan,Honglei Zhou,Heng Zhang,Deng‐Guang Yu
出处
期刊:Materials highlights
[Atlantis Press]
日期:2020-01-01
卷期号:1 (1-2): 14-14
被引量:15
标识
DOI:10.2991/mathi.k.200825.001
摘要
More and more useful drug controlled release profiles have been reported in literature for potential applications of "efficacious, safe and convenient" drug delivery [1][2][3][4][5][6][7][8][9].These profiles include immediate release, pulsatile release, delayed release, sustained release, zero-order kinetic release, dual-stage release, and multiple-phase release in terms of the drug release rate and initiating time [10][11][12][13][14][15][16][17].Among these profiles, dual-stage release is composed of a first rapid release for quickly eliminating the uncomfortable symptoms (such as ache, fever and depression) and a later sustained release for a long time period to considerably reduce the administration times [18][19][20][21].This controlled release profile holds the advantages of both pulsatile release and sustained release, and thus has a high patient compliance.
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