经颅直流电刺激
认知
睡眠剥夺对认知功能的影响
物理医学与康复
心理学
基本认知任务
临床研究设计
脑刺激
安慰剂
神经刺激
医学
神经科学
听力学
刺激
临床试验
替代医学
病理
作者
Marian E. Berryhill,Donel Martin
出处
期刊:Journal of Ect
[Ovid Technologies (Wolters Kluwer)]
日期:2018-09-01
卷期号:34 (3): e25-e35
被引量:55
标识
DOI:10.1097/yct.0000000000000534
摘要
Abstract Transcranial direct current stimulation (tDCS) is a neuromodulatory approach that is affordable, safe, and well tolerated. This review article summarizes the research and clinically relevant findings from meta-analyses and studies investigating the cognitive effects of tDCS in healthy and clinical populations. We recapitulate findings from recent studies where cognitive performance paired with tDCS was compared with performance under placebo (sham stimulation) in single sessions and longitudinal designs where cognitive effects were evaluated following repeated sessions. In summary, the tDCS literature currently indicates that the effects of tDCS on cognitive measures are less robust and less predictable compared with the more consistent effects on motor outcomes. There is also a notable difference in the consistency of single-session and longitudinal designs. In single-session tDCS designs, there are small effects amid high variability confounded by individual differences and potential sham stimulation effects. In contrast, longitudinal studies provide more consistent benefits in healthy and clinical populations, particularly when tDCS is paired with a concurrent task. Yet, these studies are few in number, thereby impeding design optimization. While there is good evidence that tDCS can modulate cognitive functioning and potentially produce longer-term benefits, a major challenge to widespread translation of tDCS is the absence of a complete mechanistic account for observed effects. Significant future work is needed to identify a priori responders from nonresponders for every cognitive task and tDCS protocol.
科研通智能强力驱动
Strongly Powered by AbleSci AI