Choline Phosphokinase, Phosphorylcholine Cytidyltransferase and CDP-choline: 1, 2-diglyceride Cholinephosphotransferase Activity in Developing Rat Lung

CHIDA, N., HIRONO, H., NISHIMURA, Y. and ARAKAWA, Ts., Choline Phosphokinase, Phosphorylcholine Cytidyltransferase and CDP-choline-1, 2-diglyceride Cholinephosphotransferase Activity in Developing Rat Lung. Tohoku J. exp. Med., 1973, 110 (3), 273-282-Incorporation of choline-methyl-14C into phosphorylcholine, CDP-choline, and phosphatidylcholine by lung tissue of developing rats was studied. Choline phosphokinase, phosphorylcholine cytidyltransferase, and CDP-choline: 1, 2-diglyceride choline phosphotransferase were determined in the lung tissue of developing rats. Results indicated that phosphorylcholine cytidyltransferase was the rate-limiting enzyme in the reactions-choline→phosphoryl-choline→CDP-choline→phosphatidylcholine