医学
重症监护医学
冲程(发动机)
临床试验
缺血性中风
闭塞
生活质量(医疗保健)
心脏病学
缺血
内科学
工程类
机械工程
护理部
作者
Michelle Kameda-Smith,Akshat Pai,Youngkyung Jung,Taylor R Duda,Brian van Adel
标识
DOI:10.1615/critrevbiomedeng.2022042563
摘要
Acute ischemic stroke (AIS) is a significant cause of global morbidity and mortality, with functional implications for quality of life and long-term disability. The limitations of intravenous thrombolytic therapy for the treatment of AIS, especially for emergent large vessel occlusion (ELVO), have paved the way for alternative therapies and the rapidly evolving landscape of endovascular therapy (EVT). Here, we summarize the major landmark trials that have advanced the field largely due to ongoing biomedical engineering device development that have translated into significantly improved clinical outcomes. Our review describes the clinical success of EVT, and current and future trends.
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