Covalent organic framework-based assembly systems for the intracellular delivery of proteins: opportunities and challenges

共价键 细胞内 纳米技术 计算机科学 化学 计算生物学 材料科学 生物化学 生物 有机化学
作者
Shengnan Zhou,Danyou Hu,Zhirui Fang,Shan Gao
出处
期刊:Nanomedicine [Future Medicine]
卷期号:16 (15): 1259-1262 被引量:3
标识
DOI:10.2217/nnm-2021-0062
摘要

NanomedicineVol. 16, No. 15 EditorialCovalent organic framework-based assembly systems for the intracellular delivery of proteins: opportunities and challengesShengnan Zhou, Danyou Hu, Zhirui Fang & Guiyang ZhangShengnan ZhouDepartment of Pharmacology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China, Danyou HuDepartment of Pharmacology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China, Zhirui FangDepartment of Pharmacology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China & Guiyang Zhang *Author for correspondence: E-mail Address: guiyangzhang@ahmu.edu.cnhttps://orcid.org/0000-0002-0569-2777Department of Pharmacology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, ChinaPublished Online:14 May 2021https://doi.org/10.2217/nnm-2021-0062AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: COF-polymercovalent organic frameworks (COFs)noncarriersprotein intracellular deliveryReferences1. 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Commun. 9, 2785 (2018).Crossref, Medline, Google Scholar20. Zhang G, Jiang B, Wu C et al. Thin platelet-like COF nanocomposites for blood brain barrier transport and inhibition of brain metastasis from renal cancer. J. Mater. Chem. B 8, 4475–4488 (2020).Crossref, Medline, CAS, Google Scholar21. Zhang G, Ji Y, Li X et al. Polymer–covalent organic frameworks composites for glucose and pH dual-responsive insulin delivery in mice. Adv. Healthc. Mater. 9(14), 2000221 (2020).Crossref, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByCharacteristic Synthesis of a Covalent Organic Framework and Its Application in Multifunctional Tumor Therapy19 December 2021 | ACS Applied Bio Materials, Vol. 5, No. 1 Vol. 16, No. 15 Follow us on social media for the latest updates Metrics Downloaded 234 times History Received 16 February 2021 Accepted 12 March 2021 Published online 14 May 2021 Published in print June 2021 Information© 2021 Future Medicine LtdKeywordsCOF-polymercovalent organic frameworks (COFs)noncarriersprotein intracellular deliveryFinancial & competing interests disclosureThis work was supported by the colleges and universities in Anhui Province Natural Science Research Projects (KJ2019A0942). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the preparation of this manuscript.PDF download
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