[Clinical diagnosis and treatment of optic nerve glioma: a review].

Optic nerve glioma (ONG) is a relatively rare central nervous system tumor that mainly affects children and adolescents. It can be classified into sporadic and neurofibromatosis type 1 (NF1)-associated types. The histological type is mainly a low-grade pilocytic astrocytoma. The typical clinical manifestations are visual impairment and painless eye protrusion, and the imaging features mainly present as fusiform swelling or irregular masses. Chemotherapy is still the first-line treatment for ONG, and other treatment options include radiotherapy, surgical resection, and molecular targeted therapy. Screening and monitoring of NF1 patients are also crucial. The prognosis of ONG is difficult to predict, and close monitoring and timely effective intervention are necessary.视神经胶质瘤（ONG）是一种相对罕见的中枢神经系统肿瘤，好发于儿童和青少年，可分为散发型和神经纤维瘤病1型（NF1）相关型。病理学类型主要为低级别的毛细胞星形细胞瘤。其典型临床表现为视力下降和无痛性眼球突出，影像学主要表现为梭形膨大或不规则肿块。化学治疗目前仍然是ONG的一线治疗方式，其他治疗方式包括放射治疗、手术切除、分子靶向治疗等，NF1患者的筛查和监测也非常重要。ONG的预后难以预测，需要对患者进行密切监测和及时有效的干预。.