化学
四氢异喹啉
硝基
组合化学
药理学
立体化学
有机化学
医学
烷基
作者
Adinarayana Nandikolla,Yogesh Mahadu Khetmalis,G. Sangeetha,Ala Chandu,Swati Swati,Muthyala Murali Krishna Kumar,Vivek Sharma,Sankaranarayanan Murugesan,Kondapalli Venkata Gowri Chandra Sekhar
摘要
We designed, synthesized, & tested 26 novel tetrahydroisoquinoline carbohydrazides for their anti-TB activity. NFT-12, 19 & 20 are the most active ones with MIC 0.78 μg mL −1 . These compounds exhibited synergism with INH in drug combination studies.
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