肌原纤维
细胞生物学
磷酸化
生物
脱甲基酶
氧化磷酸化
β氧化
化学
脂肪酸
组蛋白
生物化学
DNA
作者
Manisha Deogharia,Leslye Venegas-Zamora,Akanksha Agrawal,Miusi Shi,Abhinav K. Jain,Kevin J. McHugh,Francisco Altamirano,Ali J. Marian,Priyatansh Gurha
摘要
KDM5 inhibition enhances maturation of iPSC-CMs by epigenetically upregulating the expressions of OXPHOS, FAO, and sarcomere genes and enhancing myofibril organization and mitochondrial function.
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