Research Progress of Rac1 and Cdc42 in Tumor

The research of Rho protein family have a large progress,among which RhoA,Rac1,Cdc42 are attracting more attention from people. most people pay attention to.These G protein with low molecular weight have the GTP enzymatic activity,which participate the regulation of cell cycle and genetic transcription.They also play the vital role in the adjustment of cystoskeleton,cell movement,apoptosis,cell malignant transformation and infiltration and,metastasis of tumor.