Objective To investigate the vale of MSCT in diagnosis of cause of acute abdomen.Methods 137 cases with acute abdomen by MSCT were analyzed retrospectively.Results MSCT have a higher accuracy to diagnosis the acute abdomen.The area of the diseases were discovered and among 137 cases the cases corresponding to the clinical diagnosis were 119,the diagnostic accuracy was 86.8%.Conclusion MSCT is a rapid、simple imaging technique with high diagnostc accuracy.It is most effective image diagnosis method in acute abdomen.It plays an important role in clinical diagnosis and treatment of acute abdomen.