An efficient catalytic system for N-arylation reactions on heterogeneous copper reduced Graphene based catalyst(Cu-rGO) was described. The as-prepared catalyst was characterized by a variety of techniques,including Fourier transform infrared spectroscopy(FT-IR),X-ray photoelectron spectroscopy(XPS),X-ray diffraction(XRD),etc. The results showed that the high activity was obtained by low dosage of catalyst,and 0. 5 mol% of the catalyst was sufficient. The catalyst could be reused for 3 times without significant loss in activity,and also showed high catalytic activity with a wide variety of substituents.