Influence of kenacort-A on chroma values on hypertrophic scar tissue

Objective To investigate the efficacy of Kenacort-A on hypertrophic scar by measuring the chroma value of hypertrophic scar before and after Kenacort-A treatments. Methods Thirty-six patients with hypertrophic scar were enrolled in an own controll study. Two masses of scars taken consecutively on the same area of every patient and the masses of scars were divided into therapy group and control group. The scars in the therapy group were administrated with 1% Kenacort-A injection 4 mg/cm2 for 4 times injection with 2 weeks intervals. The scars in the control group received equal doses of lidocaine injection for 4 times with 2 weeks intervals. Chroma values of both groups were determined by Spectrophotometer CM-2600 d before and after treatments at 4 weeks, and Vancouver scar scores were used to synthetically evaluated the scars at the same time. Results All the patients were followed up for 1 to 3 months. Physiological symptoms of itch and aching in therapy group were relieved, hyperaemia of scar tissue were lessened and scar color turned light. The L values increased, the a values and the Vancouver scar scores decreased, which had statistical significance compared with those before treatment (P0.01). In control group, the post-treatment chroma values weren′t statistical significant different from the pre-treatment values (P0.05). There were significant differences between the therapy group and the control groups regarding the changes of every chroma values (P0.01). Conclusion Chroma values of hypertrophic scar tissue changed significantly after Kenacort-A treatments, therefore, Kenacort-A is one of the effective drugs for hypertrophic scar.