合理设计
圣杯
模板
聚合物
序列(生物学)
重组DNA
计算生物学
DNA
蛋白质设计
纳米技术
蛋白质工程
结构生物学
蛋白质结构
生物
化学
计算机科学
材料科学
生物化学
基因
万维网
有机化学
酶
作者
Tara D. Sutherland,Mickey G. Huson,Trevor D. Rapson
标识
DOI:10.1016/j.jsb.2017.10.012
摘要
Sequence-definable polymers are seen as a prerequisite for design of future materials, with many polymer scientists regarding such polymers as the holy grail of polymer science. Recombinant proteins are sequence-defined polymers. Proteins are dictated by DNA templates and therefore the sequence of amino acids in a protein is defined, and molecular biology provides tools that allow redesign of the DNA as required. Despite this advantage, proteins are underrepresented in materials science. In this publication we investigate the advantages and limitations of using proteins as templates for rational design of new materials.
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