Soybean diacylglycerol oil-based diet impacts lipid levels by altering the gut microbiota in C57BL/6J mice

genus. Moreover, soybean DAG-rich oils increased the levels of several gut microbial metabolites, including indole-3-proponic acid, cholic acid and ursodeoxycholic acid, in host intestinal luminal content and blood circulation, and these differential metabolites were significantly positively correlated with several altered gut strains and were mostly involved in bile acid excretion, branched-chain amino acid metabolism and lipid regulation. Our findings suggest that the DAG-rich diet may partially control host body weight and lipid levels by shaping the healthy gut ecology and regulating the levels of several gut microbial metabolites.