Dehydrative/Decarboxylative Coupling of Carboxylic Acids with Allylic Alcohols

Herein reported is a dehydrative/decarboxylative coupling reaction of carboxylic acids with allylic alcohols, which is co-catalyzed by photoredox and palladium catalysts. α-Hetero- or aryl-substituted carboxylic acids and allylic alcohols, which are both readily available, directly participate in C–C bond formation without any functional group transformation. Herein reported is a dehydrative/decarboxylative coupling reaction of carboxylic acids with allylic alcohols, which is co-catalyzed by photoredox and palladium catalysts. α-Hetero- or aryl-substituted carboxylic acids and allylic alcohols, which are both readily available, directly participate in C–C bond formation without any functional group transformation.