卵清蛋白
支气管肺泡灌洗
免疫学
哮喘
医学
细胞因子
肺
支气管高反应性
发病机制
酸性鞘磷脂酶
鞘磷脂
呼吸道疾病
内科学
抗原
胆固醇
作者
Svenja Böll,Sebastian Ziemann,Kim Ohl,Patricia Klemm,Annette D. Rieg,Erich Gulbins,Katrin Anne Becker,Markus Kamler,Norbert Wagner,Stefan Uhlig,Christian Martin,Klaus Tenbrock,Eva Verjans
出处
期刊:Allergy
[Wiley]
日期:2019-09-08
卷期号:75 (3): 603-615
被引量:20
摘要
Asm deficiency could induce higher numbers of TH 2 cells in the lung, but those cells release decreased TH 2 cytokine levels. Hereby, Asm-/- animals are protected from bronchial asthma, which possibly offers novel therapeutic strategies, for example, with ASM blockade.
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