Facile preparation of CoMoO4 nanorods at macroporous carbon hybrid electrocatalyst for non-enzymatic glucose detection

• Nanorod-like CoMoO 4 at MPC supports were prepared by a simple method. • CoMoO 4 /MPC hybrids were acted as an effective sensing platform for non-enzymatic glucose detection. • The novel CoMoO 4 /MPC hybrids will hold promise in development of electrode materials. Glucose is a popular biosensor target due to its closely with diabetes or hypoglycemia in blood. Designing efficiency electrocatalysts for the determination of glucose is vital to develop glucose detection devices. CoMoO 4 , as a kind of bimetallic oxide material, exhibits unique electrochemical properties. 3D macroporous carbon (MPC) has large specific surface area and excellent electrical conductivity, providing an effective support for loading other nano-entities to form novel composite with good synergetic effects. Herein, nanorod-like CoMoO 4 anchored onto MPC support was synthesized for the development of a promising electrochemical sensing platform for glucose. Attributing to the synergic effects between the good electrocatalytic performance of CoMoO 4 nanorods and the extraordinary electrical conductivity of 3D layered MPC, the novel CoMoO 4 /MPC composites non-enzymatic sensor shows excellent electrocatalytic performance for oxidation of glucose. Under the optimum conditions, the proposed CoMoO 4 /MPC hybrids provided a reliable linear range of 5 × 10 −7 to 1.08 × 10 −4 M with a low limit of detection (0.13 μM) for the detection of glucose. Meanwhile, the CoMoO 4 /MPC sensing platform shows fast response time of 1.76 s, good stability and selectivity for detecting glucose. Moreover, this non-enzymatic sensor also has been successfully applied to measure glucose level in human blood samples. Therefore, the developed sensor holds a new promise for the construction of facile and sensitive non-enzymatic glucose analytical platform.