The Mystery of Jejudo in Cholangiocarcinoma and chronic Clonorchis sinensis Infection

In spite of the negligible prevalence of Clonorchis sinensis infection in Jejudo, the incidence rates in intrahepatic and extrahepatic cholangiocarcinomas(CCA) in women who resided in Jejudo showed the first order in Korea. This fact would bring a chance to evaluate some risk factors of CCA because approximately 10% of CCA in Korea were allegedly caused by chronic Clonorchis sinensis infections.