Research on the Mechanism of Traditional Chinese Medicine in Treating Chemotherapy Induced Peripheral Neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is characterized by numbness, paresthesia and hyperalgesia at the extremities. It is a common side effect of tumor therapy and the main cause of tumor treatment failure and poor quality of life. Duloxetine is the only first-line drug recommended by the latest CIPN treatment guidelines, but its efficacy is not ideal. Modern studies show that CIPN pathogenesis is numerous, and the treatment of CIPN is still limited to a single mechanism and the treatment effect is not ideal. Clinical practice observed that Chinese medicine treatment CIPN patients can obviously alleviate pain, and modern pharmacological studies show that Chinese medicine can alleviate CIPN symptoms through a variety of mechanisms, this study on the CIPN protection mechanism and Chinese medicine treatment CIPN mechanism to do a summary.